“It is found that simultaneous knockdown of these master regulators can revert colorectal cancer cells into normal-like enterocytes.
By synergistically inducing differentiation and suppressing malignancy.” Experiments on mice with malignant tumours.
Were subsequently used to validate the findings of the digital study. “The fact that cancer cells can be converted back to normal cells is an astonishing phenomenon,”
Professor Kwang-Hyun Cho remarked in reference to the study.This work demonstrates that it is possible to systematically generate such reversal.
