Furthermore, naturally occurring substances that function as laxatives include N-alkanoyl-5-hydroxytryptamides,
a molecule that is closely connected to the neurotransmitter serotonin. These substances cause the colon’s water content and colonic muscle contractions to rise.
“The combination of these compounds can cause a sudden urge to use the restroom in some people,
but they also make a great natural remedy for constipation.” How can you lessen the negative effects of coffee on your stomach?
Dr. Ahmad advises cutting down on coffee as a first step if you have trouble managing it because of its effects
on your digestive system. “Avoid having it on an empty stomach, or experiment with different kinds of coffee,” he advises.