These results invited a clear question: might increasing CB1 activity with low doses of anything like THC undo this drop? The goal of the researchers in this most recent study was just this.
Their questions included how THC might influence mTOR, a protein controlling cell division, survival, and metabolism. The signaling of this protein has been connected both to aging and cognitive ability.
Working with Hebrew University in Israel, scientists from University Hospital Bonn (UKB) and the University of Bonn studied a group of male mice either 4 months old (young) or 18 months old (old).
Over a 28-day period, these test individuals were paired randomly either with a modest dose of THC or a placebo.
The scientists concentrated on particular areas, including brain function, the degree of synaptic signal between particular proteins, and the general metabolic condition of the mice.
The scientists tracked the mice’s weight, activity levels, and food consumption throughout the trial in addition to examining their biochemistry including brain biochemistry, blood plasma, and fat in their organs.
