This let them observe how THC affected their metabolace and mTOR signaling. Particularly in their hippocampal area, the older mice demonstrated a transient but notable rise in mTOR activity, according the findings.
Learning and memory depend on this part. Concurrent with the rise in mTOR activity was a higher concentration of synaptic proteins, which are essential for establishing fresh synapse connections.
“We have now been able to show that treatment with THC has a tissue-dependent and dual effect on mTOR signaling and the metabolome.”
Researcher Dr Andras Bilkei-Gorzo of the Institute of Molecular Psychiatric at the UKB stated in a release.
The medication surprisingly also improved the general metabolic conditions of the animals and reduced mTOR levels in their adipose tissue.
Often observed in low-calorie diets or following significant physical activity, this was accompanied by a drop in the levels of amino acids and carbohydrate metabolites in the plasma.
